BicOverlapper 2.0: visual analysis for gene expression

Bioinformatics. 2014 Jun 15;30(12):1785-6. doi: 10.1093/bioinformatics/btu120. Epub 2014 Mar 3.

Abstract

Motivation: Systems biology demands the use of several point of views to get a more comprehensive understanding of biological problems. This usually leads to take into account different data regarding the problem at hand, but it also has to do with using different perspectives of the same data. This multifaceted aspect of systems biology often requires the use of several tools, and it is often hard to get a seamless integration of all of them, which would help the analyst to have an interactive discourse with the data.

Results: Focusing on expression profiling, BicOverlapper 2.0 visualizes the most relevant aspects of the analysis, including expression data, profiling analysis results and functional annotation. It also integrates several state-of-the-art numerical methods, such as differential expression analysis, gene set enrichment or biclustering.

Availability and implementation: BicOverlapper 2.0 is available at: http://vis.usal.es/bicoverlapper2

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Computer Graphics
  • Gene Expression Profiling / methods*
  • Software*
  • Systems Biology / methods