Effect of fluoride gels supplemented with sodium trimetaphosphate on enamel erosion and abrasion: in vitro study

Arch Oral Biol. 2014 Mar;59(3):336-40. doi: 10.1016/j.archoralbio.2013.12.007. Epub 2013 Dec 28.

Abstract

Objective: This in vitro study aims to evaluate the effect of low fluoride (F) gel associate sodium trimetaphosphate (TMP) on erosion with or without abrasion.

Design: Enamel blocks (4 mm × 4 mm) selected through surface hardness (SH) is divided into five groups (n=12): gel without F and TMP (placebo), gel containing 4500 ppm F (4500), gel containing 4500 ppm F plus TMP5% (4500 TMP5%), gel containing 9000 ppm F (9000), and gel containing 12,300 ppm F (acid gel). Those groups were additionally subdivided into conditions of erosion (Ero) and of erosion plus abrasion (Ero/Abra). The blocks have undergone a single application of gel on the first day of the study. The erosion challenge was produced by Sprite Zero for five minutes four times a day and abrasion was carried out by machine brushing for 15s. After the challenges, the surface hardness (%SH), wear and cross-sectional hardness (ΔKHN) were analyzed. The data were analyzed using a 2-way ANOVA test followed by a Student-Newman-Keuls (p<0.05).

Results: Lower values of %SH, wear and ΔKHN were observed for erosion challenge (p<0.001). The %SH was lower in groups treated with fluoride gels, differing in the placebo (p<0.05). With addition of TMP to the gel 4500, enamel wear was lower when compared with another groups (p<0.05).

Conclusion: In vitro conditions, the 4500 5%TMP gel showed greatest effect against erosion and erosion/abrasion.

Keywords: Dental enamel; Fluoride gels; Polyphosphates; Tooth abrasion; Tooth erosion; Topical fluorides.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Cariostatic Agents / pharmacology*
  • Cattle
  • Dental Enamel / drug effects*
  • Fluorides, Topical / pharmacology*
  • Gels
  • Hardness
  • Hydrogen-Ion Concentration
  • In Vitro Techniques
  • Polyphosphates / pharmacology*
  • Surface Properties
  • Tooth Abrasion / prevention & control*
  • Tooth Erosion / prevention & control*

Substances

  • Cariostatic Agents
  • Fluorides, Topical
  • Gels
  • Polyphosphates
  • trimetaphosphoric acid