Abstract
The chromogenic βLacta test developed for the rapid detection of β-lactamase-hydrolyzing extended-spectrum cephalosporins in Enterobacteriaceae revealed good performance with extended-spectrum β-lactamase (ESBL) producers (97.5% true-positive results). However, false-negative results occurred with chromosomal AmpC hyperproducers and plasmid AmpC producers, whereas uninterpretable results were mostly due to VIM-1 carbapenemase producers and possibly low levels of expressed ESBLs.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Bacterial Proteins / genetics
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Cephalosporins / pharmacology*
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Enterobacteriaceae / drug effects*
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Enterobacteriaceae / genetics*
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Enterobacteriaceae Infections / diagnosis*
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Enterobacteriaceae Infections / drug therapy
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Enterobacteriaceae Infections / microbiology*
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Hydrolysis
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Microbial Sensitivity Tests / methods
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beta-Lactamases / genetics*
Substances
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Bacterial Proteins
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Cephalosporins
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beta-Lactamases
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carbapenemase