Abstract
A series of tunable and regenerable biomimetic hydrogen sources, 4,5-dihydropyrrolo[1,2-a]quinoxalines, have been synthesized and applied in biomimetic asymmetric hydrogenation of 3-aryl-2H-benzo[b][1,4]oxazines and 1-alkyl-3-aryl-quinoxalin-2(1H)-ones, providing the chiral amines with up to 92% and 89% ee, respectively.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Amines / chemistry
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Benzoxazines / chemical synthesis*
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Benzoxazines / chemistry
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Biomimetics
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Catalysis
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Hydrogen / chemistry
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Hydrogenation
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Molecular Structure
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Pyrroles / chemical synthesis*
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Pyrroles / chemistry
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Quinoxalines / chemistry*
Substances
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Amines
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Benzoxazines
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Pyrroles
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Quinoxalines
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Hydrogen