Pleural effusion and sarcoidosis: an unusual combination
Arch Bronconeumol. 2014 Dec;50(12):554-6.
doi: 10.1016/j.arbres.2013.07.020.
Epub 2014 Feb 22.
[Article in
English,
Spanish]
Affiliations
- 1 Servicio de Neumología, Complejo Hospitalario Clínico-Universitario de Santiago, Santiago de Compostela, La Coruña, España.
- 2 Servicio de Análisis Clínicos, Complejo Hospitalario Clínico-Universitario de Santiago, Santiago de Compostela, La Coruña, España; Grupo Interdisciplinar de Investigación en Neumología, Instituto de Investigaciones Sanitarias de Santiago (IDIS), Santiago de Compostela, La Coruña, España.
- 3 Servicio de Neumología, Complejo Hospitalario Clínico-Universitario de Santiago, Santiago de Compostela, La Coruña, España; Grupo Interdisciplinar de Investigación en Neumología, Instituto de Investigaciones Sanitarias de Santiago (IDIS), Santiago de Compostela, La Coruña, España.
- 4 Servicio de Neumología, Complejo Hospitalario Clínico-Universitario de Santiago, Santiago de Compostela, La Coruña, España; Grupo Interdisciplinar de Investigación en Neumología, Instituto de Investigaciones Sanitarias de Santiago (IDIS), Santiago de Compostela, La Coruña, España. Electronic address: luis.valdes.cuadrado@sergas.es.
Abstract
Pleural involvement in sarcoidosis is uncommon and appears in several forms. To document the incidence and characteristics of pleural effusion in sarcoidosis patients, a review of the cases diagnosed in our centre between January 2001 and December 2012 was carried out. One hundred and ninety-five patients with sarcoidosis were identified; three (two men and one woman) presented with unilateral pleural effusion (1.5%): one in the right side and two in the left. Two were in stageii and one was in stageiv. The pleural fluid of the two patients who underwent thoracocentesis was predominantly lymphocytic. One of these patients presented chylothorax and the other had high CA-125levels. In general, these effusions are lymphocyte-rich, paucicellular, serous exudates (sometimes chylothorax) and contain proportionally higher levels of protein than LDH. Most cases are treated with corticosteroids, although it may resolve spontaneously.
Keywords:
Chylothorax; Derrame pleural; Pleural effusion; Quilotórax; Sarcoidosis.
Copyright © 2013 SEPAR. Published by Elsevier Espana. All rights reserved.
MeSH terms
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Adrenal Cortex Hormones / therapeutic use
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Adult
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Aged
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Aged, 80 and over
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Chylothorax / etiology
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Female
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Humans
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Incidence
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Male
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Middle Aged
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Pleural Effusion / epidemiology
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Pleural Effusion / etiology*
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Prevalence
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Remission Induction
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Retrospective Studies
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Sarcoidosis / complications*
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Sarcoidosis / diagnosis
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Sarcoidosis / drug therapy