Nephrolithiasis by Corynebacterium urealyticum infection: literature review and case report

J Nephrol. 2014 Apr;27(2):117-25. doi: 10.1007/s40620-014-0064-1. Epub 2014 Feb 22.

Abstract

Introduction: Alkaline-encrusted cystitis or pyelonephritis is a chronic inflammatory condition due to deposition of crystals usually caused by urea-splitting bacteria. Corynebacterium urealyticum (CU) is a gram-positive, urea-splitting and multi-antibiotic resistant bacillus with special tropism for the urinary tract and it is often associated with encrusted pyelocystitis.

Methods and results: Here we report the case of a 75-year-old Caucasian man with a prolonged history of renal stones who was admitted for gross hematuria associated with renal failure. A diagnosis of encrusted pyelocystitis due to CU infection was made and the patient was appropriately treated.

Conclusions: At 6-month follow-up the patient was in good general conditions and asymptomatic. Signs of urinary tract infection or of renal calculosis were still detectable.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Aged
  • Anti-Bacterial Agents / therapeutic use
  • Corynebacterium Infections* / diagnosis
  • Corynebacterium Infections* / drug therapy
  • Humans
  • Male
  • Nephrolithiasis / diagnosis
  • Nephrolithiasis / microbiology*
  • Nephrolithiasis / therapy
  • Nephrostomy, Percutaneous
  • Pyelocystitis / diagnosis
  • Pyelocystitis / microbiology*
  • Pyelocystitis / therapy
  • Stents
  • Therapeutic Irrigation

Substances

  • Anti-Bacterial Agents