Unexpected diagnosis of peripheral schwannoma on 18F-fluoroethylcholine PET/CT for localization of prostate cancer recurrence and biopsy under real-time PET/ultrasound fusion guidance

Clin Nucl Med. 2014 Apr;39(4):385-6. doi: 10.1097/RLU.0000000000000375.

Abstract

18F-Fluoroethylcholine (18F-FEC) PET/CT is well established for the detection of prostate cancer recurrence. However, its specificity is sometimes impaired by false-positive findings. In the present case, atypical cancer recurrence in the right distal lower leg was suspected on 18F-FEC PET/CT in a patient with a history of prostate cancer and an increased prostate-specific antigen level. Using a real-time PET/ultrasound fusion technique, the tumor was localized and a biopsy carried out, leading to a final diagnosis of peripheral schwannoma.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Choline / analogs & derivatives*
  • Humans
  • Image Processing, Computer-Assisted*
  • Image-Guided Biopsy
  • Incidental Findings
  • Male
  • Multimodal Imaging*
  • Neurilemmoma / diagnosis*
  • Neurilemmoma / diagnostic imaging
  • Neurilemmoma / pathology*
  • Positron-Emission Tomography
  • Prostatic Neoplasms / diagnosis*
  • Prostatic Neoplasms / diagnostic imaging
  • Prostatic Neoplasms / pathology*
  • Recurrence
  • Tomography, X-Ray Computed
  • Ultrasonography

Substances

  • fluoroethylcholine
  • Choline