Background: Wound myiasis in the Indian subcontinent is most commonly caused by old world screw-worm (Chrysomya bezziana).
Case report and management: A 4-year-old malnourished girl presented with full thickness rectal prolapse following acute diarrhea with a large wound and screwworm myiasis of the rectum. Turpentine oil was applied to immobilize the maggots followed by manual extraction. Prolapse was successfully treated by manual reduction followed by strapping of the buttocks.
Outcome: Child was thriving well and gained 2 kg weight in follow up after two weeks.
Message: Parents should be educated about taking care of prolapsed rectum.