Abstract
Two new flavone glycosides, 3″-O-acetyl-7-O-methylvitexin (1) and 6″-α-rhamnopyranosyl-7-O-methylvitexin (2), along with nine known compounds (3-11) were isolated from the leaves of Rhabdophyllum arnoldianum (Ochnaceae). The structures of the new compounds were established by detailed spectroscopic studies and mass spectrometry, while known compounds were characterised by direct comparison of their reported NMR data with those found in the literature. All these compounds were the first reported from Rhabdophyllum genus. The biological assays on crude extracts and compounds of this plant demonstrated that the crude extracts possess significant antimicrobial activity against Gram-positive bacteria.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Anti-Bacterial Agents / chemistry
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Anti-Bacterial Agents / isolation & purification*
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Anti-Bacterial Agents / pharmacology
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Bacillus cereus / drug effects
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Bacillus subtilis / drug effects
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Cameroon
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Enterococcus faecalis / drug effects
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Flavones / chemistry
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Flavones / isolation & purification*
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Flavones / pharmacology
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Glycosides / chemistry
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Glycosides / isolation & purification*
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Glycosides / pharmacology
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Gram-Positive Bacteria / drug effects
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Microbial Sensitivity Tests
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Nuclear Magnetic Resonance, Biomolecular
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Ochnaceae / chemistry*
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Plant Leaves / chemistry
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Staphylococcus aureus / drug effects
Substances
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3'-O-acetyl-7-O-methylvitexin
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6'-alpha-rhamnopyranosyl-7-O-methylvitexin
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Anti-Bacterial Agents
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Flavones
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Glycosides