Phenobarbital-induced pellagra resulted in death

Cutan Ocul Toxicol. 2014 Mar;33(1):76-8. doi: 10.3109/15569527.2013.800546. Epub 2013 Jun 12.

Abstract

Pellagra is caused by deficiency of niacin or its precursor tryptophan. While cutaneous lesions are the most prominent feature of the disease, gastrointestinal, neurological and psychiatric signs and symptoms are the other characteristics of the disease. In this case report, we present a 29-year-old female patient with discoloration of hands and feet diagnosed with pellagra.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Anticonvulsants / administration & dosage
  • Anticonvulsants / adverse effects*
  • Anticonvulsants / therapeutic use
  • Dermatitis / blood
  • Dermatitis / drug therapy
  • Dermatitis / etiology*
  • Fatal Outcome
  • Female
  • Humans
  • Niacin / administration & dosage
  • Niacin / blood
  • Niacin / therapeutic use
  • Pellagra / blood
  • Pellagra / chemically induced*
  • Pellagra / complications
  • Pellagra / drug therapy
  • Phenobarbital / administration & dosage
  • Phenobarbital / adverse effects*
  • Phenobarbital / therapeutic use
  • Seizures / drug therapy

Substances

  • Anticonvulsants
  • Niacin
  • Phenobarbital