Abstract
The antimicrobial activities of longan (Dimocarpus longan Lour. Fen ke) seed extracts were investigated using a disc diffusion method and also determining the minimal inhibitory concentration. The DL-P01-SI01 fraction showed that the strongest activity against Staphylococcus aureus and methicillin-resistant S. aureus at MIC 64 μg/mL, which was found to be due to the phenolic compounds. The HPLC analysis showed that the major phenolic compounds are gallic acid, corilagin, ethyl gallate and ellagic acid.
Keywords:
Antimicrobial activity; corilagin; ellagic acid; ethyl gallate; longan seed.
MeSH terms
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Acinetobacter baumannii / drug effects
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Anti-Infective Agents / pharmacology*
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Cell Line
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Cell Survival / drug effects
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Chromatography, High Pressure Liquid
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Ellagic Acid / pharmacology
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Gallic Acid / analogs & derivatives
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Gallic Acid / pharmacology
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Glucosides / pharmacology
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Humans
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Hydrolyzable Tannins
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Keratinocytes / cytology
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Keratinocytes / drug effects
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Methicillin-Resistant Staphylococcus aureus / drug effects
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Microbial Sensitivity Tests
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Phenols / pharmacology
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Plant Extracts / pharmacology*
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Propionibacterium acnes / drug effects
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Salmonella / drug effects
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Sapindaceae / chemistry*
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Seeds / chemistry*
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Staphylococcus aureus / drug effects
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Streptococcus mutans / drug effects
Substances
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Anti-Infective Agents
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Glucosides
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Hydrolyzable Tannins
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Phenols
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Plant Extracts
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Ellagic Acid
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ethyl gallate
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corilagin
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Gallic Acid