Acute myeloid leukemia cells harboring MLL fusion genes or with the acute promyelocytic leukemia phenotype are sensitive to the Bcl-2-selective inhibitor ABT-199

Affiliations

• ¹ National Engineering Laboratory for AIDS Vaccine, Key Laboratory for Molecular Enzymology & Engineering, the Ministry of Education, School of Life Sciences, Jilin University, Changchun, China.
• ² 1] National Engineering Laboratory for AIDS Vaccine, Key Laboratory for Molecular Enzymology & Engineering, the Ministry of Education, School of Life Sciences, Jilin University, Changchun, China [2] Department of Pediatrics, Wayne State University School of Medicine, Detroit, MI, USA.
• ³ Department of Pediatric Hematology and Oncology, The First Hospital of Jilin University, Changchun, China.
• ⁴ 1] Wayne State University School of Medicine, Detroit, MI, USA [2] Cancer Biology Graduate Program, Wayne State School of Medicine, Detroit, MI, USA.
• ⁵ 1] Department of Oncology, Wayne State University School of Medicine, Detroit, MI, USA [2] Molecular Therapeutics Program, Barbara Ann Karmanos Cancer Institute, Wayne State University School of Medicine, Detroit, MI, USA.
• ⁶ 1] National Engineering Laboratory for AIDS Vaccine, Key Laboratory for Molecular Enzymology & Engineering, the Ministry of Education, School of Life Sciences, Jilin University, Changchun, China [2] Department of Oncology, Wayne State University School of Medicine, Detroit, MI, USA [3] Molecular Therapeutics Program, Barbara Ann Karmanos Cancer Institute, Wayne State University School of Medicine, Detroit, MI, USA.
• ⁷ 1] Department of Pediatrics, Wayne State University School of Medicine, Detroit, MI, USA [2] Molecular Therapeutics Program, Barbara Ann Karmanos Cancer Institute, Wayne State University School of Medicine, Detroit, MI, USA [3] Division of Pediatric Hematology/Oncology, Children's Hospital of Michigan, Detroit, MI, USA.
• ⁸ Department of Hematology and Oncology, The First Hospital of Jilin University, Changchun, China.