Successful containment and infection control of a Carbapenem-resistant Klebsiella pneumoniae outbreak in an Italian hospital

Paolo Gaibani; Rosaria Colombo; Milena Arghittu; Lisa Cariani; Simone Ambretti; Gloria Bua; Donatella Lombardo; Maria Paola Landini; Erminio Torresani; Vittorio Sambri

Successful containment and infection control of a Carbapenem-resistant Klebsiella pneumoniae outbreak in an Italian hospital

New Microbiol. 2014 Jan;37(1):87-90. Epub 2014 Jan 15.

Authors

Paolo Gaibani¹, Rosaria Colombo, Milena Arghittu, Lisa Cariani, Simone Ambretti, Gloria Bua, Donatella Lombardo, Maria Paola Landini, Erminio Torresani, Vittorio Sambri

Affiliation

¹ Operative Unit of Clinical Microbiology, Regional Reference Centre for Microbiological Emergencies (CRREM), St.Orsola-Malpighi University Hospital, Bologna, Italy.

PMID: 24531175

Abstract

We describe an outbreak of a carbapenemase-producing Klebsiella pneumoniae sequence type 258 (ST258) clone in an Italian hospital during two months in 2010. The rapid detection and management of the eleven patients colonized and infected with KPC-producing K.pneumoniae curbed the spread of this multidrug-resistant organism.

MeSH terms

Anti-Bacterial Agents / therapeutic use*
Bacterial Proteins
Carbapenems / therapeutic use*
Containment of Biohazards
Cross Infection / drug therapy*
Cross Infection / epidemiology
Cross Infection / microbiology
Cross Infection / prevention & control
Disease Outbreaks
Drug Resistance, Bacterial*
Hospitals
Humans
Infection Control
Italy / epidemiology
Klebsiella Infections / drug therapy*
Klebsiella Infections / epidemiology
Klebsiella Infections / microbiology
Klebsiella Infections / prevention & control
Klebsiella pneumoniae / drug effects*
Klebsiella pneumoniae / genetics
Klebsiella pneumoniae / isolation & purification
beta-Lactamases

Substances

Anti-Bacterial Agents
Bacterial Proteins
Carbapenems
beta-Lactamases
carbapenemase