Aggregatibacter aphrophilus brain abscess secondary to primary tooth extraction: Case report and literature review

J Microbiol Immunol Infect. 2016 Feb;49(1):119-22. doi: 10.1016/j.jmii.2013.12.007. Epub 2014 Feb 12.

Abstract

We report on a rare case of Aggregatibacter aphrophilus brain abscess of odontogenic origin in a 6-year-old previously healthy boy, who had close contact with a pet dog. The poodle was the most likely source of the infecting organism, which subsequently colonized the patient's oral cavity. The abscess was surgically removed and he recovered completely after prolonged antibiotic treatment with meropenem. We also review the relevant medical literature on A. aphrophilus pediatric brain abscesses.

Keywords: Aggregatibacter aphrophilus; Brain abscess; Canine transmission; Odontogenic origin.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Aggregatibacter aphrophilus / isolation & purification*
  • Animals
  • Anti-Bacterial Agents / administration & dosage
  • Brain Abscess / diagnosis*
  • Brain Abscess / microbiology
  • Brain Abscess / pathology*
  • Brain Abscess / therapy
  • Child
  • Debridement
  • Dogs
  • Humans
  • Male
  • Pasteurellaceae Infections / diagnosis*
  • Pasteurellaceae Infections / microbiology
  • Pasteurellaceae Infections / pathology*
  • Pasteurellaceae Infections / therapy
  • Tooth Extraction / adverse effects*
  • Tooth, Deciduous
  • Treatment Outcome

Substances

  • Anti-Bacterial Agents