Coexistence of Wolff-Parkinson-white and Brugada syndrome: mere curiosity?

Ann Noninvasive Electrocardiol. 2014 Sep;19(5):504-7. doi: 10.1111/anec.12124. Epub 2014 Feb 12.

Abstract

The association between Brugada syndrome (BS) and ventricular preexcitation is a rare condition, with sporadic cases already reported. We report the case of a 29-year-old man, with palpitation unrelated to physical or emotional stress. The electrocardiogram of the first visit revealed a ventricular preexcitation pattern and an end-conduction delay, with negative T wave in V1 and intraventricular conduction disturbance in V2 (atypical for BS). The typical aspect of BS occurred after introduction of propafenone for the prevention of atrioventricular tachycardia. We discuss the recognition of this rare association, the proarrhythmic effects of some drugs, treatment options, and prognosis.

Keywords: Brugada syndrome; Wolff-Parkinson-White syndrome; arrhythmias.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Brugada Syndrome / complications*
  • Brugada Syndrome / physiopathology
  • Brugada Syndrome / surgery
  • Catheter Ablation
  • Electrocardiography
  • Humans
  • Male
  • Prognosis
  • Wolff-Parkinson-White Syndrome / complications*
  • Wolff-Parkinson-White Syndrome / physiopathology
  • Wolff-Parkinson-White Syndrome / surgery