Abstract
A Pd-mediated direct C-H bond functionalisation of tryptophan has been developed, both as a single amino acid residue and within peptides. Important mechanistic insight into this process has been gained by characterising a Pd catalytically competent nanoparticle phase which evolves during the early stages of reaction.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Catalysis
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Fluorescent Dyes / chemical synthesis*
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Fluorescent Dyes / chemistry
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Palladium / chemistry*
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Peptides / chemical synthesis*
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Peptides / chemistry
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Tryptophan / analogs & derivatives
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Tryptophan / chemical synthesis*
Substances
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Fluorescent Dyes
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Peptides
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Palladium
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Tryptophan