Statistical study on the incidence of allergic diseases treated with desloratadine and levocetirizine at "Atopia" Allergology Medical Center, Iaşi, Romania

Rev Med Chir Soc Med Nat Iasi. 2013 Oct-Dec;117(4):1021-7.

Abstract

Allergies and allergic manifestations are a major health problem in our country and around the world. Epidemiological data have reported an increased incidence of allergic diseases up to 10-30% over the past decades.

Aim: To evaluate the incidence of the most common allergic diseases treated with desloratadine or levocetirizine, second-generation antihistamines.

Material and methods: For diagnosis and assessment of treatment with the two antihistamines the following tests were performed: allergy skin testing, immunoglobulin E blood levels, evaluation of target organ for allergic reaction (lung function tests, nasal and conjunctival examination, assessment of bronchial inflammation).

Results: We conducted a retrospective study that included 365 patients (64% women and 36% men) diagnosed with different types of allergy in the "Atopia" Allergology Medical Center at Iaşi during the interval August 2012-August 2013. Patients were aged 2 to 90 years (mean age group 35.98 years; 39.55 years for women, and 29.74 years for men).

Conclusions: The majority of patients were from urban areas (82%). The most common allergic diseases in the study group were: urticaria (21%), allergic rhinoconjunctivitis (14%), allergic bronchitis (14%) and allergic asthma (12%).

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Asthma / drug therapy
  • Biomarkers / blood
  • Cetirizine / therapeutic use*
  • Child
  • Child, Preschool
  • Conjunctivitis, Allergic / drug therapy
  • Female
  • Histamine H1 Antagonists, Non-Sedating / therapeutic use*
  • Humans
  • Hypersensitivity / blood
  • Hypersensitivity / diagnosis
  • Hypersensitivity / drug therapy*
  • Hypersensitivity / epidemiology
  • Immunoglobulin E / blood
  • Incidence
  • Loratadine / analogs & derivatives*
  • Loratadine / therapeutic use
  • Male
  • Retrospective Studies
  • Rhinitis, Allergic, Perennial / drug therapy
  • Rhinitis, Allergic, Seasonal / drug therapy
  • Romania / epidemiology
  • Skin Tests
  • Treatment Outcome
  • Urticaria / drug therapy

Substances

  • Biomarkers
  • Histamine H1 Antagonists, Non-Sedating
  • Immunoglobulin E
  • levocetirizine
  • Loratadine
  • desloratadine
  • Cetirizine