Narrow-rim functionalization of calix[4]arene through Ugi-4CR: synthesis of a series of calix[4]arene peptoids

Anupriya Savithri; Sreeja Thulasi; Ramavarma Luxmi Varma

doi:10.1021/jo4025732

Narrow-rim functionalization of calix[4]arene through Ugi-4CR: synthesis of a series of calix[4]arene peptoids

J Org Chem. 2014 Feb 21;79(4):1683-9. doi: 10.1021/jo4025732. Epub 2014 Feb 11.

Authors

Anupriya Savithri¹, Sreeja Thulasi, Ramavarma Luxmi Varma

Affiliation

¹ Chemical Sciences and Technology Division and ‡Academy of Scientific and Innovative Research (AcSIR), National Institute for Interdisciplinary Science and Technology (NIIST)-CSIR , Trivandrum 695019, India.

PMID: 24498973
DOI: 10.1021/jo4025732

Abstract

Adaptation of Ugi-4CR for the narrow-rim modification of calix[4]arene toward the synthesis of a series of tripeptoid and tetrapeptoid calix[4]arenes is described. The metal ion/organic cation binding properties of the newly synthesized peptoid calix[4]arenes were also investigated.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Aldehydes / chemistry*
Calixarenes / chemical synthesis*
Calixarenes / chemistry*
Magnetic Resonance Spectroscopy
Peptoids / chemical synthesis*
Peptoids / chemistry
Phenols / chemical synthesis
Phenols / chemistry*

Substances

Aldehydes
Peptoids
Phenols
calix(4)arene
Calixarenes