Terpenoid indole alkaloids from Mappianthus iodoides Hand.-Mazz

Hai-Jian Cong; Qing Zhao; Shu-Wei Zhang; Jiao-Jiao Wei; Wen-Qiong Wang; Li-Jiang Xuan

doi:10.1016/j.phytochem.2014.01.004

Terpenoid indole alkaloids from Mappianthus iodoides Hand.-Mazz

Phytochemistry. 2014 Apr:100:76-85. doi: 10.1016/j.phytochem.2014.01.004. Epub 2014 Feb 1.

Authors

Hai-Jian Cong¹, Qing Zhao¹, Shu-Wei Zhang¹, Jiao-Jiao Wei¹, Wen-Qiong Wang¹, Li-Jiang Xuan²

Affiliations

¹ State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 501 Haike Road, Zhangjiang Hi-Tech Park, Shanghai 201203, PR China.
² State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 501 Haike Road, Zhangjiang Hi-Tech Park, Shanghai 201203, PR China. Electronic address: ljxuan@mail.shcnc.ac.cn.

PMID: 24495957
DOI: 10.1016/j.phytochem.2014.01.004

Abstract

Ten terpenoid indole alkaloids, mappiodines A-C and mappiodosides A-G, together with eight known compounds, were isolated from stems of Mappianthus iodoides Hand.-Mazz. Their structures were elucidated by spectroscopic analyses including 1D, 2D NMR, MS and CD methods. The ten compounds were evaluated for their cytotoxic activity, but were inactive.

Keywords: Icacinaceae; Mappianthus iodoides; Terpenoid indole alkaloid.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Secologanin Tryptamine Alkaloids / chemistry*
Secologanin Tryptamine Alkaloids / isolation & purification
Secologanin Tryptamine Alkaloids / metabolism
Spectrum Analysis
Tracheophyta / chemistry*
Tracheophyta / metabolism

Substances

Secologanin Tryptamine Alkaloids