Nonsynonymous variant Pro70Ser (rs117648444) in IFNL4 gene identifies carriers of the rs368234815 ΔG allele with higher HCV RNA decline during the first 4 weeks of pegylated interferon and ribavirin therapy in HCV-1 patients

J Clin Virol. 2014 Apr;59(4):274-5. doi: 10.1016/j.jcv.2014.01.006. Epub 2014 Jan 18.
No abstract available

Publication types

  • Letter

MeSH terms

  • Alleles
  • Drug Therapy, Combination / methods
  • Hepatitis C, Chronic / drug therapy*
  • Humans
  • Interferons / therapeutic use*
  • Interleukins / genetics*
  • Polymorphism, Single Nucleotide*
  • RNA, Viral / blood
  • Ribavirin / therapeutic use*
  • Treatment Outcome
  • Viral Load*

Substances

  • IFNL4 protein, human
  • Interleukins
  • RNA, Viral
  • Ribavirin
  • Interferons