Core/shell nanoparticles in biomedical applications

Adv Colloid Interface Sci. 2014 Jul:209:8-39. doi: 10.1016/j.cis.2013.12.008. Epub 2014 Jan 14.

Abstract

Nanoparticles have several exciting applications in different areas and biomedial field is not an exception of that because of their exciting performance in bioimaging, targeted drug and gene delivery, sensors, and so on. It has been found that among several classes of nanoparticles core/shell is most promising for different biomedical applications because of several advantages over simple nanoparticles. This review highlights the development of core/shell nanoparticles-based biomedical research during approximately past two decades. Applications of different types of core/shell nanoparticles are classified in terms of five major aspects such as bioimaging, biosensor, targeted drug delivery, DNA/RNA interaction, and targeted gene delivery.

Keywords: Bioimaging; Biomedical; Core/shell nanoparticles; Drug delivery; MRI.

Publication types

  • Review

MeSH terms

  • Animals
  • Biocompatible Materials / chemistry*
  • Biosensing Techniques
  • Contrast Media / chemistry
  • DNA / chemistry
  • Dose-Response Relationship, Drug
  • Drug Delivery Systems*
  • Gene Transfer Techniques
  • Humans
  • Magnetic Resonance Imaging
  • Metals / chemistry
  • Mice
  • Nanoparticles / chemistry*
  • Nanotechnology / methods*
  • Optics and Photonics
  • Polymers / chemistry
  • Quantum Dots
  • RNA / chemistry
  • Rats
  • Solvents
  • Tomography, X-Ray Computed
  • Transfection

Substances

  • Biocompatible Materials
  • Contrast Media
  • Metals
  • Polymers
  • Solvents
  • RNA
  • DNA