Carcinosarcoma of the Female Urethra

Urol Int. 2016;96(3):370-2. doi: 10.1159/000355089. Epub 2014 Jan 30.

Abstract

Carcinosarcoma is a rare malignant tumor with a biphasic morphology characterized by the presence of a malignant epithelial and mesenchymal component. It has been reported in many organs, including the genitourinary tract. We describe a case of a 47-year-old woman admitted to our hospital for history of recurrent urinary tract infection, dysuria and discharge of bloody fluid from the urethra at the end of urination. A tender palpable mass under the anterior vaginal wall was found and pathological examination showed a urethral carcinosarcoma. The histopathogenetic hypothesis and clinical management were considered in this report.

Publication types

  • Case Reports

MeSH terms

  • Carcinosarcoma / diagnosis*
  • Carcinosarcoma / mortality
  • Carcinosarcoma / pathology*
  • Cisplatin / administration & dosage
  • Fatal Outcome
  • Female
  • Humans
  • Magnetic Resonance Imaging
  • Middle Aged
  • Neoadjuvant Therapy / methods
  • Neoplasm Recurrence, Local
  • Polyploidy
  • Positron-Emission Tomography
  • Ureteral Neoplasms / diagnosis*
  • Ureteral Neoplasms / mortality
  • Ureteral Neoplasms / pathology*
  • Urethra / pathology*

Substances

  • Cisplatin