Abstract
In this communication, we describe a novel synthetic method for fabricating multicomponent gold nanoparticles containing both gallium ions and biomolecules on the surface. Detailed compositional analysis, using STEM-HAADF and EELS spectroscopy, confirmed the crystalline nature of gold and chelation of gallium ions. The presence of the biomolecule was validated using conventional ELISA.
Publication types
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Research Support, Non-U.S. Gov't
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Research Support, U.S. Gov't, Non-P.H.S.
MeSH terms
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Cell Line, Tumor
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Cell Survival / drug effects
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Chelating Agents / chemistry*
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Chelating Agents / pharmacology
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Gallium / chemistry*
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Gallium / pharmacology
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Gold / chemistry*
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Gold / pharmacology
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Humans
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Metal Nanoparticles / administration & dosage
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Metal Nanoparticles / chemistry*
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Pentetic Acid / chemistry*
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Pentetic Acid / pharmacology
Substances
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Chelating Agents
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Gold
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Pentetic Acid
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Gallium