Application of machine learning techniques to analyse the effects of physical exercise in ventricular fibrillation

Comput Biol Med. 2014 Feb:45:1-7. doi: 10.1016/j.compbiomed.2013.11.008. Epub 2013 Nov 27.

Abstract

This work presents the application of machine learning techniques to analyse the influence of physical exercise in the physiological properties of the heart, during ventricular fibrillation. To this end, different kinds of classifiers (linear and neural models) are used to classify between trained and sedentary rabbit hearts. The use of those classifiers in combination with a wrapper feature selection algorithm allows to extract knowledge about the most relevant features in the problem. The obtained results show that neural models outperform linear classifiers (better performance indices and a better dimensionality reduction). The most relevant features to describe the benefits of physical exercise are those related to myocardial heterogeneity, mean activation rate and activation complexity.

Keywords: Classification; Extreme learning machine; Knowledge extraction; Logistic regression; Machine learning; Multilayer perceptron; Physical exercise; Ventricular fibrillation.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Artificial Intelligence
  • Electrocardiography / classification
  • Male
  • Physical Conditioning, Animal / physiology*
  • Physical Fitness / physiology*
  • Rabbits
  • Signal Processing, Computer-Assisted*
  • Ventricular Fibrillation / classification
  • Ventricular Fibrillation / physiopathology*