[Analysis of salvianolate injection combined with usual drugs in treatment of coronary heart disease in real world]

Zhongguo Zhong Yao Za Zhi. 2013 Sep;38(18):3186-9.
[Article in Chinese]

Abstract

Objective: Based on real world research the circumstances of the clinical use of usual drugs combined with salvianolate injection are surveyed.

Method: Descriptive statistics on the use of salvianolate injection in 18 general hospitals in China.

Result: In 1 605 patients with coronary heart disease (CHD), salvianolate injection was most frequently (51%) combined with clopidogrel and isosorbide dinitrate. In addition this combination showed a higher clinical effectiveness as compared with other drug combinations.

Conclusion: In the real world, salvianolate injection combined with usual treatment was found to be more effective than other treatment combinations. In addition practice conformed to the clinical treatment of coronary heart disease (CHD) guidelines for drug use. However, liver and kidney function, routine blood tests and the blood's coagulation function require ongoing monitoring.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Aged, 80 and over
  • Clopidogrel
  • Coronary Disease / drug therapy*
  • Coronary Disease / mortality
  • Drug Therapy, Combination
  • Drugs, Chinese Herbal / administration & dosage*
  • Female
  • Hospital Information Systems / statistics & numerical data
  • Humans
  • Isosorbide Dinitrate / therapeutic use*
  • Male
  • Middle Aged
  • Plant Extracts / administration & dosage*
  • Pragmatic Clinical Trials as Topic
  • Propensity Score
  • Ticlopidine / analogs & derivatives*
  • Ticlopidine / therapeutic use
  • Treatment Outcome

Substances

  • Drugs, Chinese Herbal
  • Plant Extracts
  • salvianolate
  • Clopidogrel
  • Isosorbide Dinitrate
  • Ticlopidine