[Outcome study on parenterally administered shenfu in treatment of coronary heart disease]

Zhongguo Zhong Yao Za Zhi. 2013 Sep;38(18):3099-103.
[Article in Chinese]

Abstract

Objective: To understand the clinical circumstances for the use of parenterally administered Shenfu in the treatment of coronary heart disease, in order to provide a reference guide for its clinical use.

Method: Information was extracted and summarized on the treatment of coronary heart disease patients, who received parenterally administered Shenfu, from 20 nationwide general hospitals HIS data. Descriptive statistical methods were used to analyze the usage and dosage. Correlation analysis was adopted to analyze information including drug combinations, and outcomes were compared with other combinations.

Result: Real world HIS data showed that the drug delivery method for parenterally administered Shenfu was intravenous infusion. Treatment courses were from 3 to7 days, at a dosage of 60 mL. The drug combination was mostly with chemical drugs. The most common combinations were Shenfu plus clopidogrel, aspirin and isosorbide dinitrate.

Conclusion: Parenterally administered Shenfu is a common drug used in the treatment of coronary heart disease. Most of the usage was in accordance with instructions. The chemical combination drugs were mainly clopidogrel, aspirin and isosorbide dinitrate.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Aspirin / therapeutic use
  • Coronary Disease / drug therapy*
  • Drug Therapy, Combination
  • Drugs, Chinese Herbal / administration & dosage*
  • Drugs, Chinese Herbal / adverse effects
  • Female
  • Hospital Information Systems / statistics & numerical data
  • Humans
  • Infusions, Parenteral
  • Isosorbide Dinitrate / therapeutic use
  • Male
  • Middle Aged
  • Outcome Assessment, Health Care*
  • Pragmatic Clinical Trials as Topic

Substances

  • Drugs, Chinese Herbal
  • Shen-Fu
  • Isosorbide Dinitrate
  • Aspirin