Cancer statistics: current diagnosis and treatment of pancreatic cancer in Shanghai, China

Jiang Long; Guo-pei Luo; Zhi-wen Xiao; Zu-qiang Liu; Meng Guo; Liang Liu; Chen Liu; Jin Xu; Yu-tang Gao; Ying Zheng; Chunxiao Wu; Quan-xing Ni; Min Li; Xianjun Yu

doi:10.1016/j.canlet.2014.01.004

Cancer statistics: current diagnosis and treatment of pancreatic cancer in Shanghai, China

Cancer Lett. 2014 May 1;346(2):273-7. doi: 10.1016/j.canlet.2014.01.004. Epub 2014 Jan 21.

Authors

Jiang Long¹, Guo-pei Luo¹, Zhi-wen Xiao¹, Zu-qiang Liu¹, Meng Guo¹, Liang Liu¹, Chen Liu¹, Jin Xu¹, Yu-tang Gao², Ying Zheng³, Chunxiao Wu³, Quan-xing Ni¹, Min Li⁴, Xianjun Yu⁵

Affiliations

¹ Department of Pancreatic and Hepatobiliary Surgery, Fudan University Shanghai Cancer Center, Shanghai 200032, PR China; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai 200032, PR China; Pancreatic Cancer Institute, Fudan University, Shanghai 200032, PR China.
² Department of Epidemiology, Shanghai Cancer Institute, Shanghai 200032, PR China.
³ Department of Oncology, Shanghai Center for Disease Control and Prevention, Shanghai 200336, PR China.
⁴ Department of Pancreatic and Hepatobiliary Surgery, Fudan University Shanghai Cancer Center, Shanghai 200032, PR China; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai 200032, PR China; Pancreatic Cancer Institute, Fudan University, Shanghai 200032, PR China; The Vivian L. Smith Department of Neurosurgery, The University of Texas Medical School at Houston, Houston, TX 77030, USA. Electronic address: min.li@uth.tmc.edu.
⁵ Department of Pancreatic and Hepatobiliary Surgery, Fudan University Shanghai Cancer Center, Shanghai 200032, PR China; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai 200032, PR China; Pancreatic Cancer Institute, Fudan University, Shanghai 200032, PR China. Electronic address: yuxianjun88@hotmail.com.

PMID: 24462819
DOI: 10.1016/j.canlet.2014.01.004

Abstract

A multi-center population-based study in Shanghai, China was performed to explore the implications for the management of pancreatic cancer by comparing diagnosis and survival rates. Novel imaging modalities including MRI (13.9%), PET/CT (1.8%), and EUS (5.6%) were not widely used in our population. Only 39.7% of cases were histologically verified (surgery with histologic diagnosis 31.0%, cytological diagnosis 8.7%, surgery without histologic diagnosis 12.1%, and clinical diagnosis 48.2%). Overall, 30.0% of patients underwent curative-intent operation, and only 9.8% of patients received comprehensive treatment. The prognosis of pancreatic cancer patients was significantly better for patients who were treated in high-volume centers than in low-volume centers. We propose that more effort should be put on novel diagnostic modalities, histological confirmation, and comprehensive treatment in China. Multidisciplinary teams specialized in pancreatic cancer therapy in high-volume centers are urgently needed.

Keywords: Pancreatic cancer; Prognosis; Shanghai; Survival.

Publication types

Multicenter Study
Research Support, Non-U.S. Gov't

MeSH terms

Adult
Age Factors
Aged
Case-Control Studies
China / epidemiology
Female
Humans
Incidence
Male
Middle Aged
Pancreatic Neoplasms / diagnosis
Pancreatic Neoplasms / epidemiology*
Pancreatic Neoplasms / mortality
Pancreatic Neoplasms / therapy
Sex Factors