Background uptake of breast-specific gamma imaging: correlation with mammographic breast density and background enhancement of breast MRI

Clin Imaging. 2014 May-Jun;38(3):255-8. doi: 10.1016/j.clinimag.2013.05.010. Epub 2014 Jan 22.

Abstract

Purpose: To investigate the relationship between background uptake of breast-specific gamma imaging (BSGI) mammographic breast density and background enhancement of breast magnetic resonance imaging (MRI).

Materials and methods: The level and texture of background uptake of BSGI, mammographic breast density, and background enhancement of breast MRI are retrospectively reviewed in 104 patients.

Results: Heterogeneous and increased background uptake of BSGI was significantly correlated with high mammographic breast density (P=.016, P=.001) and increased background enhancement of breast MRI (P=.015, P=.017).

Conclusion: Interpreting BSGI of women showing high mammographic breast density or background enhancement of breast MRI needs to be carried out with caution.

Keywords: Breast density; Breast-specific gamma imaging; MRI.

MeSH terms

  • Adult
  • Aged
  • Breast / pathology
  • Breast Neoplasms / diagnostic imaging*
  • Breast Neoplasms / pathology
  • Female
  • Gamma Rays*
  • Humans
  • Magnetic Resonance Imaging / methods
  • Mammography / methods*
  • Middle Aged
  • Radiographic Image Enhancement
  • Retrospective Studies
  • Sensitivity and Specificity