Abstract
The rhodium-catalyzed oxidative alkenylation of N-benzyltriflamides with olefins followed by an intramolecular cyclization via C-H bond activation is described. This method results in the direct and efficient synthesis of highly substituted isoindoline frameworks.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Benzylamines / chemistry*
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Catalysis
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Cyclization
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Isoindoles / chemical synthesis*
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Isoindoles / chemistry
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Molecular Structure
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Organometallic Compounds / chemistry*
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Rhodium / chemistry*
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Sulfonamides / chemistry*
Substances
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Benzylamines
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Isoindoles
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Organometallic Compounds
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Sulfonamides
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Rhodium