Analysis of new biomarkers for cholangiocarcinoma

J Hepatobiliary Pancreat Sci. 2014 Jun;21(6):397-8. doi: 10.1002/jhbp.69. Epub 2014 Jan 21.

Abstract

Cholangiocarcinoma is one of the most serious diseases in northeast Thailand, where its incidence is reported to be the highest in the world. We tried to develop a new method to detect cholangiocarcinoma in the early stages using serum proteins. We found that after fluorescent labeling of the sugar moiety of serum proteins, a new peak was identified, which might be a promising marker for cholangiocarcinoma.

Keywords: Biliary tract cancer · Cholangiocarcinoma · Opisthorchis viverrini · Tumor marker.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Bile Duct Neoplasms / blood*
  • Bile Duct Neoplasms / diagnosis
  • Bile Ducts, Intrahepatic
  • Biomarkers, Tumor / blood*
  • Blood Proteins / analysis
  • Blood Proteins / metabolism*
  • Case-Control Studies
  • Cholangiocarcinoma / blood*
  • Cholangiocarcinoma / diagnosis
  • Cohort Studies
  • Female
  • Humans
  • Male
  • Sensitivity and Specificity
  • Thailand

Substances

  • Biomarkers, Tumor
  • Blood Proteins