Epithelioid hemangioma of the testis

Indian J Pathol Microbiol. 2013 Oct-Dec;56(4):422-4. doi: 10.4103/0377-4929.125359.

Abstract

Testicular hemangioma is a very rare benign vascular neoplasm, there are only less than 30 cases of testicular hemangiomas reported in the literature. We report a case of epithelioid hemangioma of the testis in a 53-year-old man who presented with painless mass in the right testis. An orchiectomy was performed, The 1 cm tumor was composed of prominent proliferation of small, capillary-sized vessels lined by plump, epithelioid endothelial cells. Immunohistochemically, the epithelioid endothelial cells reacted with antibodies to factor VIII-related antigen, CD31, CD34 and Vimentin, but not CK, EMA, CEA, S-100 and CD68. Although it is a rare tumor, we should be aware of it and avoid confusion with other vascular neoplasm.

Publication types

  • Case Reports

MeSH terms

  • Antigens, CD34 / analysis
  • Factor VIII / analysis
  • Hemangioma / diagnosis*
  • Hemangioma / pathology*
  • Hemangioma / surgery
  • Histocytochemistry
  • Humans
  • Immunohistochemistry
  • Male
  • Microscopy
  • Middle Aged
  • Orchiectomy
  • Platelet Endothelial Cell Adhesion Molecule-1 / analysis
  • Testicular Neoplasms / diagnosis*
  • Testicular Neoplasms / pathology*
  • Testicular Neoplasms / surgery
  • Testis / pathology*
  • Vimentin / analysis

Substances

  • Antigens, CD34
  • Platelet Endothelial Cell Adhesion Molecule-1
  • Vimentin
  • Factor VIII