Distinctive spontaneous regional neural activity in patients with somatoform pain disorder: a preliminary resting-state fMRI study

Atsuo Yoshino; Yasumasa Okamoto; Yoshihiko Kunisato; Shinpei Yoshimura; Ran Jinnin; Yumi Hayashi; Makoto Kobayakawa; Mitsuru Doi; Kyoko Oshita; Ryuji Nakamura; Keisuke Tanaka; Hidehisa Yamashita; Masashi Kawamoto; Shigeto Yamawaki

doi:10.1016/j.pscychresns.2013.12.006

Distinctive spontaneous regional neural activity in patients with somatoform pain disorder: a preliminary resting-state fMRI study

Psychiatry Res. 2014 Mar 30;221(3):246-8. doi: 10.1016/j.pscychresns.2013.12.006. Epub 2014 Jan 2.

Authors

Affiliations

¹ Department of Psychiatry and Neurosciences, Division of Frontier Graduate School of Biomedical Sciences, Hiroshima University, 1-2-3 Kasumi, Minami-ku, Hiroshima 734-8551, Japan. Electronic address: yoshino@hiroshima-u.ac.jp.
² Department of Psychiatry and Neurosciences, Division of Frontier Graduate School of Biomedical Sciences, Hiroshima University, 1-2-3 Kasumi, Minami-ku, Hiroshima 734-8551, Japan.
³ Department of Psychology, School of Human Sciences, Senshu University, 2-1-1, Higashi-Mita, Tama, Kawasaki 214-8580, Japan.
⁴ Department of Psychology, Otemon Gakuin University, 2-1-15 Nishiai Ibaraki Osaka 567-8502, Japan.
⁵ Department of Dental Anesthesiology, Hiroshima University, 1-2-3 Kasumi, Minami-ku, Hiroshima 734-8551, Japan.
⁶ Department of Anesthesiology and Critical Care, Hiroshima University, 1-2-3 Kasumi, Minami-ku, Hiroshima 734-8551, Japan.
⁷ Graduate School of Integrated Arts and Sciences, Hiroshima University, 1-7-1 Kagamiyama, Higashi-Hiroshima 739-8521, Japan.

PMID: 24439113
DOI: 10.1016/j.pscychresns.2013.12.006

Abstract

This resting-state functional magnetic resonance imaging study found that nine patients with somatoform pain disorder exhibited atypical precentral gyrus activation compared with 20 healthy controls. The role of the precentral gyrus in pain-related processing is discussed.

Keywords: Precentral gyrus; Resting-state fMRI; Somatoform pain disorder.

Publication types

Comparative Study
Research Support, Non-U.S. Gov't

MeSH terms

Adult
Brain / pathology
Brain / physiopathology*
Female
Frontal Lobe / physiopathology
Humans
Magnetic Resonance Imaging*
Male
Middle Aged
Pain / pathology
Pain / physiopathology*
Psychophysiologic Disorders / pathology
Psychophysiologic Disorders / physiopathology*
Somatoform Disorders / pathology
Somatoform Disorders / physiopathology*