Complete Genome Sequence of Sterol-Transforming Mycobacterium neoaurum Strain VKM Ac-1815D

Victoriya Y Shtratnikova; Eugeny Y Bragin; Dmitry V Dovbnya; Yury A Pekov; Mikhail I Schelkunov; Nicolai Strizhov; Tanya V Ivashina; Vasily V Ashapkin; Marina V Donova

doi:10.1128/genomeA.01177-13

Complete Genome Sequence of Sterol-Transforming Mycobacterium neoaurum Strain VKM Ac-1815D

Genome Announc. 2014 Jan 16;2(1):e01177-13. doi: 10.1128/genomeA.01177-13.

Authors

Victoriya Y Shtratnikova¹, Eugeny Y Bragin, Dmitry V Dovbnya, Yury A Pekov, Mikhail I Schelkunov, Nicolai Strizhov, Tanya V Ivashina, Vasily V Ashapkin, Marina V Donova

Affiliation

¹ Center of Innovations and Technologies Biologically Active Compounds and Their Applications, Moscow, Russia.

Abstract

Mycobacterium neoaurum strain VKM Ac-1815D produces 4-androstene-3,17-dione as a major compound from phytosterols. Here, we report the complete genome sequence of the strain. The genome consists of a single circular 5,438,190-bp chromosome, with a G+C content of 66.88%, containing 5,318 putative open reading frames (ORFs), 46 tRNAs, and 6 rRNAs. Arrays of cholesterol metabolism genes are randomly clustered throughout the chromosome.