Activation of aryl halides at gold(I): practical synthesis of (P,C) cyclometalated gold(III) complexes

J Am Chem Soc. 2014 Feb 5;136(5):1778-81. doi: 10.1021/ja412432k. Epub 2014 Jan 23.

Abstract

Taking advantage of phosphine chelation, direct evidence for oxidative addition of Csp(2)-X bonds (X = I, Br) to a single gold atom is reported. NMR studies and DFT calculations provide insight into this unprecedented transformation, which gives straightforward access to stable (P,C) cyclometalated gold(III) complexes.