[Cellular models for individualized medicine in Alzheimer's disease using patient-derived induced pluripotent stem cells]

Nihon Yakurigaku Zasshi. 2014 Jan;143(1):23-6. doi: 10.1254/fpj.143.23.

[Article in Japanese]

Authors

Masashi Asai, Keiro Shirotani, Takayuki Kondo, Haruhisa Inoue, Nobuhisa Iwata

PMID: 24420133
DOI: 10.1254/fpj.143.23

No abstract available

Publication types

Review

MeSH terms

Alzheimer Disease / classification
Alzheimer Disease / drug therapy*
Alzheimer Disease / genetics*
Amyloid Precursor Protein Secretases / antagonists & inhibitors
Amyloid Precursor Protein Secretases / physiology
Amyloid beta-Peptides / metabolism*
Amyloid beta-Protein Precursor / genetics
Amyloid beta-Protein Precursor / metabolism
Animals
Cell Differentiation
Docosahexaenoic Acids / pharmacology
Docosahexaenoic Acids / therapeutic use
Endoplasmic Reticulum Stress / drug effects
Humans
Induced Pluripotent Stem Cells / cytology*
Induced Pluripotent Stem Cells / metabolism
Molecular Targeted Therapy*
Mutation
Neurons / metabolism*
Oxidative Stress / drug effects
Precision Medicine*
Protein Multimerization

Substances

Amyloid beta-Peptides
Amyloid beta-Protein Precursor
Docosahexaenoic Acids
Amyloid Precursor Protein Secretases