Gastritis May Boost Odds of Dementia

Am J Alzheimers Dis Other Demen. 2014 Aug;29(5):452-6. doi: 10.1177/1533317513518654. Epub 2014 Jan 8.

Abstract

Introduction: Given the high prevalence of dementia and its devastating consequences, identifying risk factors for dementia is a public health priority. The present study aims to assess whether gastritis increases the odds of dementia.

Methodology: The data for this study, consisting of 2926 community-dwelling older adults, were obtained from the National survey entitled "Mental Health and Quality of Life of Older Malaysians." Dementia was diagnosed using the Geriatric Mental State-Automated Geriatric Examination for Computer-Assisted Taxonomy.

Results: Prevalence of dementia was considerably higher among older adults with gastritis (29.5%) compared to those without gastritis (13.2%). After adjusting for age, gender, marital status, educational attainment, hypertension, stroke, and diabetes, gastritis was significantly associated with more than twice odds of dementia (adjusted odds ratio = 2.42, P < .001, 95% confidence interval = 1.68-3.49).

Conclusions: The findings from this population-based observational study showing evidence that gastritis may increase the risk of dementia provide avenue for further inquiries into dementia.

Keywords: aged; dementia; gastritis; risk factor.

Publication types

  • Observational Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Aged, 80 and over
  • Comorbidity
  • Dementia / epidemiology*
  • Female
  • Gastritis / epidemiology*
  • Humans
  • Malaysia / epidemiology
  • Male
  • Middle Aged
  • Risk Factors