Preparation of size tunable giant vesicles from cross-linked dextran(ethylene glycol) hydrogels

Chem Commun (Camb). 2014 Feb 25;50(16):1953-5. doi: 10.1039/c3cc49144g.

Abstract

We present a novel chemically cross-linked dextran-poly(ethylene glycol) hydrogel substrate for the preparation of dense vesicle suspensions under physiological ionic strength conditions. These vesicles can be easily diluted for individual study. Modulating the degree of cross-linking within the hydrogel network results in tuning of the vesicle size distribution.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Cross-Linking Reagents / chemical synthesis*
  • Cross-Linking Reagents / chemistry
  • Dextrans / chemistry*
  • Ethylene Glycol / chemistry*
  • Hydrogels / chemical synthesis*
  • Hydrogels / chemistry
  • Osmolar Concentration
  • Particle Size
  • Surface Properties

Substances

  • Cross-Linking Reagents
  • Dextrans
  • Hydrogels
  • Ethylene Glycol