The fear of malnutrition, caused by the low-protein diet, conditions in an inappropriate use of a useful nutrition therapy in Chronic Kidney Disease. Often malnutrition is due to reduced intake of energy, because a low (or very low) protein proper diet with adequate amount of calories (30-35 cal/kg bw/day). We analyze the positive aspects of the low-protein diet for optimal control of hypertension, hyperphosphatemia, anemia, and proteinuria that is the goal of pharmacological management Chronic Kidney Disease patients.