Association of prostate volume with voiding impairment and deterioration in quality of life after prostate biopsy

Urology. 2014 Mar;83(3):617-21. doi: 10.1016/j.urology.2013.11.002. Epub 2014 Jan 1.

Abstract

Objective: To evaluate how voiding function and quality of life (QoL) were affected by transrectal ultrasound-guided prostate biopsy with respect to prostatic size and to determine whether there is a size-bothersomeness relationship.

Methods: Ninety-two patients who were candidates for prostate biopsy were included. Ten-core prostate biopsies were taken, and patients were followed up for 7 days. The international prostate symptom score, QoL, maximum urine flow rate (Q-max) and average urine flow rate, postvoid residual urine, and prostate volume (Vp) of the patients were recorded at baseline and on postbiopsy day 7. On receiver operating characteristics curve analysis, a Vp of 38.8 mL was found to be the best cutoff point for deterioration in QoL after biopsy. Then, patients were divided into 2 groups according to baseline Vp, as <38.8 mL and ≥38.8 mL, group 1 and 2, respectively. Baseline and postbiopsy values were compared.

Results: One patient in group 1 and 5 in group 2 developed acute urinary retention after biopsy, but the difference was not significant (P >.05). Only Vp and Q-max of group 1 (P <.001 and P = .035, respectively), but QoL (P = .002), international prostate symptom score, Q-max, Vp (P <.001 in all 3), and average urine flow rate (P = .006) of group 2 were significantly changed on postbiopsy day 7 compared with baseline.

Conclusion: Patients with a Vp >38.8 mL were more prone to voiding difficulty and deterioration in QoL after biopsy. They should be informed about the likelihood of these complications.

Publication types

  • Clinical Trial

MeSH terms

  • Aged
  • Area Under Curve
  • Biopsy, Large-Core Needle / adverse effects*
  • Humans
  • Lower Urinary Tract Symptoms / etiology*
  • Male
  • Middle Aged
  • Organ Size
  • Prostate / diagnostic imaging
  • Prostate / pathology*
  • Prostatic Hyperplasia / pathology
  • Prostatic Neoplasms / pathology*
  • Quality of Life
  • ROC Curve
  • Surveys and Questionnaires
  • Ultrasonography, Interventional
  • Urinary Retention / etiology*
  • Urodynamics