The application of fiber-reinforced materials in disc repair

Biomed Res Int. 2013:2013:714103. doi: 10.1155/2013/714103. Epub 2013 Dec 8.

Abstract

The intervertebral disc degeneration and injury are the most common spinal diseases with tremendous financial and social implications. Regenerative therapies for disc repair are promising treatments. Fiber-reinforced materials (FRMs) are a kind of composites by embedding the fibers into the matrix materials. FRMs can maintain the original properties of the matrix and enhance the mechanical properties. By now, there are still some problems for disc repair such as the unsatisfied static strength and dynamic properties for disc implants. The application of FRMs may resolve these problems to some extent. In this review, six parts such as background of FRMs in tissue repair, the comparison of mechanical properties between natural disc and some typical FRMs, the repair standard and FRMs applications in disc repair, and the possible research directions for FRMs' in the future are stated.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Biocompatible Materials*
  • Humans
  • Intervertebral Disc / injuries*
  • Intervertebral Disc / surgery
  • Intervertebral Disc Degeneration / surgery*
  • Prostheses and Implants*
  • Regenerative Medicine / methods*

Substances

  • Biocompatible Materials