Objective: To describe the technique of isolated limb infusion (ILI) for regional high dose chemotherapy in patients with advanced malignancies confined to a limb, as currently practiced at Melanoma Institute Australia (MIA).
Background: ILI is progressively being used around the world but to date the reported response rates are generally lower than those reported by MIA.
Discussion: This description of the ILI protocol at MIA provides details that may allow other surgeons to improve results.
Keywords: in transit metastasis; isolated limb infusion; melanoma; soft tissue sarcoma; toxicity.
© 2013 Wiley Periodicals, Inc.