Clinical and microbiological efficacy of micafungin on Geosmithia argillacea infection in a cystic fibrosis patient

Med Mycol Case Rep. 2012 Sep 12;1(1):79-81. doi: 10.1016/j.mmcr.2012.08.004. eCollection 2012.

Abstract

Cystic fibrosis (CF) patients are at high risk of colonization of the airways by a number of fungi, including the emerging opportunistic fungus Geosmithia argillacea. We report the eradication of respiratory G. argillacea associated with clinical resolution of severe symptoms by high-dose and prolonged micafungin therapy in a young CF patient.

Keywords: Cystic fibrosis; Geosmithia argillacea; Micafungin; Pulmonary exacerbation.