Dedifferentiated endometrioid adenocarcinoma: An under-recognized but aggressive tumor?

Emily S Wu; Ie-Ming Shih; Teresa P Díaz-Montes

doi:10.1016/j.gynor.2013.02.007

Dedifferentiated endometrioid adenocarcinoma: An under-recognized but aggressive tumor?

Gynecol Oncol Case Rep. 2013 Mar 6:5:25-7. doi: 10.1016/j.gynor.2013.02.007. eCollection 2013.

Authors

Emily S Wu¹, Ie-Ming Shih², Teresa P Díaz-Montes³

Affiliations

¹ Department of Gynecology and Obstetrics, Johns Hopkins University School of Medicine, 600 North Wolfe Street, Phipps 279, Baltimore, MD, 21287, USA.
² Department of Gynecology and Obstetrics, Johns Hopkins University School of Medicine, 600 North Wolfe Street, Phipps 279, Baltimore, MD, 21287, USA ; Department of Pathology, Johns Hopkins University School of Medicine, 1550 Orleans Street, Baltimore, MD, 21231, USA.
³ Division of Gynecologic Oncology, Department of Gynecology and Obstetrics, Johns Hopkins University School of Medicine, 600 North Wolfe Street, Baltimore, MD, 21287, USA.

Abstract

•Dedifferentiated endometrioid adenocarcinoma is characterized by the coexistence of an undifferentiated carcinoma and a low-grade endometrioid adenocarcinoma.•Given its histological appearance, this tumor can be mistaken for other less aggressive tumors.•The possibility of undifferentiated carcinoma should be considered in endometrioid carcinoma with patterns of solid growth without appreciable glandular differentiation.

Keywords: Bone metastases; Dedifferentiated endometrioid adenocarcinoma; Uterine cancer.