Eptifibatide-Induced Thrombocytopenia--When Inhibitor Turns Killer

Am J Ther. 2016 Jan-Feb;23(1):e298-9. doi: 10.1097/01.mjt.0000438283.01797.1a.

Abstract

Eptifibatide is a commonly and widely used drug for management of acute coronary syndrome and during percutaneous coronary intervention. It is usually well tolerated with no major adverse effects. We report a rare case of life-threatening thrombocytopenia secondary to eptifibatide along with a literature review of available evidence.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Aged
  • Eptifibatide
  • Humans
  • Male
  • Peptides / adverse effects*
  • Platelet Aggregation Inhibitors / adverse effects*
  • Platelet Glycoprotein GPIIb-IIIa Complex / antagonists & inhibitors*
  • Thrombocytopenia / chemically induced*

Substances

  • Peptides
  • Platelet Aggregation Inhibitors
  • Platelet Glycoprotein GPIIb-IIIa Complex
  • Eptifibatide