Abstract
It has recently been demonstrated that patients who develop chronic illness after prior exposure to water damaged buildings (WDB) and mold have the presence of mycotoxins, which can be detected in the urine. We hypothesized that the mold may be harbored internally and continue to release and/or produce mycotoxins which contribute to ongoing chronic illness. The sinuses are the most likely candidate as a site for the internal mold and mycotoxin production. In this paper, we review the literature supporting this concept.
MeSH terms
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Adult
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Aged
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Animals
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Antifungal Agents / pharmacology
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Aspergillosis / diagnosis
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Aspergillosis / drug therapy
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Aspergillosis / metabolism
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Aspergillus niger / drug effects
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Aspergillus niger / growth & development
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Biofilms / drug effects*
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Child
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Chronic Disease
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Environmental Exposure / analysis*
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Fatigue Syndrome, Chronic / drug therapy
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Fatigue Syndrome, Chronic / microbiology
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Female
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Humans
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Male
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Mycotoxins / toxicity
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Mycotoxins / urine
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Nasal Lavage Fluid / microbiology
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Paranasal Sinuses / drug effects
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Paranasal Sinuses / microbiology*
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Rhinitis / drug therapy
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Rhinitis / microbiology
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Sinusitis / drug therapy
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Sinusitis / microbiology
Substances
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Antifungal Agents
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Mycotoxins