Abstract
This review focuses on surface-grafted DNA, and its use as a molecular building block that exploits its unique properties as a directional (poly)anion that exhibits molecular recognition. The selected examples highlight innovative applications of DNA at surfaces and interfaces ranging from molecular diagnostics and sequencing to biosensing.
Publication types
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Research Support, U.S. Gov't, Non-P.H.S.
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Review
MeSH terms
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Biosensing Techniques
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DNA / chemical synthesis
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DNA / chemistry*
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Immobilized Nucleic Acids / chemical synthesis
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Immobilized Nucleic Acids / chemistry
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Nucleic Acid Conformation
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Polyelectrolytes
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Polymers / chemistry
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Sequence Analysis, DNA
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Surface Properties
Substances
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Immobilized Nucleic Acids
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Polyelectrolytes
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Polymers
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polyanions
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DNA