Synthesis of δ-oxo-1,1-bis(triflyl)alkanes and their acidities

Hikaru Yanai; Masaya Fujita; Arata Takahashi; Min Zhang; Masaaki Mishima; Akira Kotani; Takashi Matsumoto; Takeo Taguchi

doi:10.3390/molecules181215531

Synthesis of δ-oxo-1,1-bis(triflyl)alkanes and their acidities

Molecules. 2013 Dec 13;18(12):15531-40. doi: 10.3390/molecules181215531.

Authors

Hikaru Yanai¹, Masaya Fujita, Arata Takahashi, Min Zhang, Masaaki Mishima, Akira Kotani, Takashi Matsumoto, Takeo Taguchi

Affiliation

¹ School of Pharmacy, Tokyo University of Pharmacy and Life Sciences, 1432-1 Horinouchi, Hachioji, Tokyo 192-0392, Japan. yanai@toyaku.ac.jp.

Abstract

The reaction of 1,1-bis(triflyl)ethylene generated in situ with enolizable carbonyls yielded δ-oxo-1,1-bis(triflyl)alkane derivatives. Their acidities in both the gas and solution phases were determined.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Alkanes / chemical synthesis*
Combinatorial Chemistry Techniques

Substances

Alkanes