1 Department of Intensive Care, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands, and Nijmegen Institute for Infection, Inflammation and Immunity (N4i), Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands Department of Medical Informatics, Academic Medical Centre, Amsterdam, The Netherlands Department of Medical Informatics, Academic Medical Centre, Amsterdam, The Netherlands, and National Intensive Care Evaluation, Amsterdam, The Netherlands.