In-vitro biocompatibility and corrosion resistance of strontium incorporated TiO2 nanotube arrays for orthopaedic applications

J Biomater Appl. 2014 Jul;29(1):113-29. doi: 10.1177/0885328213516821. Epub 2013 Dec 16.

Abstract

This article investigates the in-vitro biocompatibility and corrosion behaviour of strontium ion incorporated TiO2 nanotube arrays formed by anodization method for orthopaedic applications. The morphological studies were carried out using field emission scanning electron microscopy, atomic force microscopy, attenuated total reflectance fourier transform infrared spectroscopy, X-ray photoelectron spectroscopy and thin film X-ray diffraction techniques. The morphological investigation indicated that the length and the average diameter of nanotube were 2.1 ± 0.3 µm and 110 ± 4 nm, respectively. The wettability measurements showed that the TiO2 nanotube arrays have super wettability, as well as, strontium ion incorporated TiO2 nanotube arrays exhibited hydrophilic behaviour. Excellent in-vitro bioactivity was observed for TiO2 nanotube arrays with strontium ions. Electrochemical studies in Hank's solution showed that the TiO2 nanotube arrays with strontium ions have enhanced corrosion resistance.

Keywords: Anodization; Hank’s solution; TiO2 nanotubes; biocompatibility; dip coating.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Coated Materials, Biocompatible / chemistry
  • Corrosion
  • Electrochemistry
  • Humans
  • In Vitro Techniques
  • Materials Testing
  • Microscopy, Electron, Scanning
  • Nanotubes / chemistry*
  • Nanotubes / ultrastructure
  • Prostheses and Implants
  • Strontium / chemistry*
  • Surface Properties
  • Titanium / chemistry*
  • Wettability

Substances

  • Coated Materials, Biocompatible
  • titanium dioxide
  • Titanium
  • Strontium