Immunology: glyco-engineering 'super-self'

Nat Chem Biol. 2014 Jan;10(1):7-8. doi: 10.1038/nchembio.1415.

Abstract

Altered glycosylation of cancer cells confers phenotypic changes that promote spread and evasion of immune responses. A novel method for engineering cell surface glycans is providing insights into these mechanisms.

Publication types

  • News
  • Comment

MeSH terms

  • Glycocalyx / immunology*
  • Humans
  • Immune Evasion*
  • Killer Cells, Natural / immunology*
  • Sialic Acid Binding Immunoglobulin-like Lectins / physiology*

Substances

  • Sialic Acid Binding Immunoglobulin-like Lectins